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The demonstration of immune complexes within clinical lesions in other diseases has also been difficult and problematic, however, and the immune complex theory of ENL is thus neither proved nor disproved.

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Mechanism of methemoglobin formation by diphenylsulfones: effect of 4-amino-4-hydroxy amino diphenylsulfone and other p-substituted derivatives.

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Phavichitr N, Cameron DJ, Catto-Smith AG: Increasing incidence of Crohn's disease in Victorian children.

Physical assessment was repeated every 2 weeks and laboratory studies were repeated every 4 weeks during the study.

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Afdhal NH, Long A, Lennon J, Crowe J, O'Donoghue DP (1991) Controlled trial of antimycobacterial therapy in Crohn's disease.

In a study of patients receiving no myelosuppressive therapies, 8% of asymptomatic HIV-seropositive patients, 20% of those with symptomatic middle-stage HIV disease, and 71% of those with Centers for Disease Control (CDC)-defined AIDS were anemic.

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MAP US is a double blind, placebo controlled study designed to evaluate the safety and efficacy of RHB-104 compared to placebo in treating patients with moderate to severe Crohn's disease.

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Cutaneous or metastatic CD is a rare complication defined as the occurrence of specific granulomatous cutaneous lesions with the same histopathology (non-caseating granulomas with multinucleated giant cells in the dermis surrounded by lymphocytes, plasma cells, and eosinophils) as the intestinal lesions (Georgiou et al.

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The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients.

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TNBS treatment also significantly reduced colon length to 24% when compared to control group but was 97% of controls in mice also treated with turmeric.

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Using this method, a 5-year follow-up study of nerve function impairment in over 200 patients has demonstrated that nerve injury continues to be a problem even after the infection is treated and cured ().

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Non-invasive biomarkers of mucosal healing such as fecal calprotectin are particularly useful for children as a way of monitoring resolution or recurrence of intestinal inflammation, but the cutoff value in each scenario that should trigger change in management is still elusive.

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This disease poses major challenges to our understanding in microbiology, immunology, pathology, treatment, and prevention, requiring continued emphasis on basic research and clinical management in the field.

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Purpose: It has been recognized that inflammatory bowel disease (IBD) has a higher prevalence in African American populations than once thought.

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Invasion of mucosal ulcers in Crohn's disease both perpetuates inflammation and causes common septic local complications, such as abscesses and fistulae.

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Anti-CD20 chimeric monoclonal antibody treatment of refractory immune-mediated thrombocytopenia in a patient with chronic graft-versus-host disease.

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